In the land of Terra, natural disasters of unknown causes have been occurring irregularly in many areas. Therefore, the majority of the people, in order to escape those natural disasters, came to live in mobile cities developed over the years. The Originium left behind at the site of such Catastrophes, has led to the rapid progress of civilization due to their immense energy. But it also brought something else with it — an incurable disease called Oripathy. Because the bodies of those with Oripathy gradually crystalize and become a new source of infection at the time of death, in many countries, the Infected are subject to persecution under regimes of segregation and forced labor. Those who were oppressed by the governments are starting to rebel. Rhodes Island, a pharmaceutical company researching a cure for Oripathy, takes up their arms and starts a conquest trying to save all the people from the disease.

One day, Kei Kusanagi notices a strange glowing woman by the lake. He discovers that the woman is actually an alien officer from the Galaxy Federation named Mizuho Kazami, and even more shocking—she's also his teacher! In spite of this setback, he and his teacher gradually get to know each other and a romance blossoms between them. However, soon enough, the principal of the school finds out about their relationship. The solution? Get married! Together, the newlyweds must keep their marriage a secret, not only from Kei's high school friends, but also the Galaxy Federation. Onegai☆Teacher is the fragile but comedic love story of an alien and her student.

"I will definitely become the world's best Jazz player!" Blue Giant follows Dai Miyamoto, who is a member of the basketball club. While attending junior high school one day, a friend takes him to a live jazz performance, which inspires him deeply. Thereafter, he begins practicing the tenor saxophone by himself, without the ability to read sheet music. Rain or shine, day or night, Dai continues to practice. During his first performance, he is criticized by the audience, however, Dai passionately blows away at his saxophone. A tale of reaching his goal recklessly and sincerely begins.

Living amongst the rest of humanity, there is a small number of people known as "Attractors" that possess strange powers. Fearful of these dangerous mutations, a highly secretive organization named Custos uses cyborgs from a group called WTOC to exterminate Attractors before they can injure anyone or disrupt the social order. Conversely, inside the theme park Fantasium Garden, there is a hidden group of Attractors who want to save their people from being eradicated by Custos. Led by the ever-optimistic Quon Mitsuchi, the Attractors take on intense fights against Custos's WTOC in the hopes of protecting the existence of their kind.